| Opelika to Salisbury (New York) | 859.08 mi (1,382.56 km) |
| Opelika to Salisbury (North Carolina) | 347.97 mi (560.00 km) |
| Opelika to Salmon Creek (Washington) | 2,165.90 mi (3,485.69 km) |
| Opelika to Salt Lake City (Utah) | 1,566.41 mi (2,520.90 km) |
| Opelika to Sammamish (Washington) | 2,167.04 mi (3,487.51 km) |
| Opelika to San Angelo (Texas) | 885.98 mi (1,425.84 km) |
| Opelika to San Anselmo (California) | 2,114.40 mi (3,402.80 km) |
| Opelika to San Antonio (Texas) | 808.23 mi (1,300.73 km) |
| Opelika to San Benito (Texas) | 864.47 mi (1,391.22 km) |
| Opelika to San Bernardino (California) | 1,836.41 mi (2,955.42 km) |
| Opelika to San Bruno (California) | 2,107.56 mi (3,391.79 km) |
| Opelika to San Buenaventura (California) | 1,945.50 mi (3,130.97 km) |
| Opelika to San Carlos (California) | 2,098.92 mi (3,377.88 km) |
| Opelika to San Carlos Park (Florida) | 477.72 mi (768.82 km) |
| Opelika to San Clemente (California) | 1,859.91 mi (2,993.24 km) |
