| Opelika to San Diego (California) | 1,837.79 mi (2,957.64 km) |
| Opelika to San Diego Country Estates (California) | 1,816.82 mi (2,923.89 km) |
| Opelika to San Dimas (California) | 1,865.93 mi (3,002.92 km) |
| Opelika to San Fernando (California) | 1,900.25 mi (3,058.16 km) |
| Opelika to San Francisco (California) | 2,108.02 mi (3,392.52 km) |
| Opelika to San Gabriel (California) | 1,882.52 mi (3,029.63 km) |
| Opelika to San Germán (Puerto Rico) | 1,519.95 mi (2,446.12 km) |
| Opelika to San Jacinto (California) | 1,821.71 mi (2,931.76 km) |
| Opelika to San Jose (California) | 2,076.40 mi (3,341.64 km) |
| Opelika to San Juan (Puerto Rico) | 1,551.19 mi (2,496.40 km) |
| Opelika to San Juan (Texas) | 888.33 mi (1,429.63 km) |
| Opelika to San Juan Capistrano (California) | 1,862.00 mi (2,996.59 km) |
| Opelika to San Leandro (California) | 2,092.55 mi (3,367.63 km) |
| Opelika to San Lorenzo (California) | 2,091.16 mi (3,365.39 km) |
| Opelika to San Luis (Arizona) | 1,702.34 mi (2,739.65 km) |
