| Opelika to San Luis Obispo (California) | 2,019.81 mi (3,250.58 km) |
| Opelika to San Marcos (California) | 1,837.82 mi (2,957.69 km) |
| Opelika to San Marcos (Texas) | 765.76 mi (1,232.36 km) |
| Opelika to San Marino (California) | 1,883.12 mi (3,030.60 km) |
| Opelika to San Mateo (California) | 2,101.21 mi (3,381.58 km) |
| Opelika to San Pablo (California) | 2,102.06 mi (3,382.93 km) |
| Opelika to San Rafael (California) | 2,111.78 mi (3,398.59 km) |
| Opelika to San Ramon (California) | 2,080.24 mi (3,347.83 km) |
| Opelika to San Tan Valley (Arizona) | 1,515.21 mi (2,438.50 km) |
| Opelika to Sand Springs (Oklahoma) | 657.79 mi (1,058.62 km) |
| Opelika to Sandusky (Ohio) | 624.59 mi (1,005.18 km) |
| Opelika to Sandy (Oregon) | 2,143.02 mi (3,448.86 km) |
| Opelika to Sandy (Utah) | 1,559.26 mi (2,509.38 km) |
| Opelika to Sandy Springs (Georgia) | 105.57 mi (169.89 km) |
| Opelika to Sanford (Florida) | 361.74 mi (582.17 km) |
