| Opelika to Sanford (Maine) | 1,085.95 mi (1,747.67 km) |
| Opelika to Sanford (North Carolina) | 404.89 mi (651.61 km) |
| Opelika to Sanger (California) | 1,951.60 mi (3,140.80 km) |
| Opelika to Santa Ana (California) | 1,872.98 mi (3,014.28 km) |
| Opelika to Santa Barbara (California) | 1,972.04 mi (3,173.69 km) |
| Opelika to Santa Clara (California) | 2,082.82 mi (3,351.98 km) |
| Opelika to Santa Clara (Oregon) | 2,169.73 mi (3,491.84 km) |
| Opelika to Santa Clarita (California) | 1,902.75 mi (3,062.19 km) |
| Opelika to Santa Cruz (California) | 2,087.64 mi (3,359.73 km) |
| Opelika to Santa Fe (New Mexico) | 1,193.83 mi (1,921.28 km) |
| Opelika to Santa Fe (Texas) | 618.19 mi (994.89 km) |
| Opelika to Santa Fe Springs (California) | 1,881.69 mi (3,028.29 km) |
| Opelika to Santa Maria (California) | 2,009.27 mi (3,233.61 km) |
| Opelika to Santa Monica (California) | 1,904.80 mi (3,065.48 km) |
| Opelika to Santa Paula (California) | 1,935.49 mi (3,114.86 km) |
