| Opelika to Smyrna (Delaware) | 712.19 mi (1,146.16 km) |
| Opelika to Smyrna (Georgia) | 96.79 mi (155.76 km) |
| Opelika to Smyrna (Tennessee) | 237.75 mi (382.62 km) |
| Opelika to Snellville (Georgia) | 114.50 mi (184.27 km) |
| Opelika to Snoqualmie (Washington) | 2,156.71 mi (3,470.90 km) |
| Opelika to Snyder (Texas) | 902.56 mi (1,452.52 km) |
| Opelika to Socastee (South Carolina) | 374.98 mi (603.48 km) |
| Opelika to Socorro (Texas) | 1,221.72 mi (1,966.16 km) |
| Opelika to Soddy-Daisy (Tennessee) | 179.74 mi (289.26 km) |
| Opelika to Solana Beach (California) | 1,843.93 mi (2,967.53 km) |
| Opelika to Soledad (California) | 2,051.38 mi (3,301.37 km) |
| Opelika to Solon (Ohio) | 640.59 mi (1,030.92 km) |
| Opelika to Somers Point (New Jersey) | 756.69 mi (1,217.78 km) |
| Opelika to Somerset (Kentucky) | 308.61 mi (496.66 km) |
| Opelika to Somerset (New Jersey) | 810.03 mi (1,303.62 km) |
