| Opelika to Stephenville (Texas) | 749.13 mi (1,205.60 km) |
| Opelika to Sterling (Colorado) | 1,127.38 mi (1,814.34 km) |
| Opelika to Sterling (Illinois) | 674.37 mi (1,085.30 km) |
| Opelika to Sterling (Virginia) | 625.22 mi (1,006.20 km) |
| Opelika to Sterling Heights (Michigan) | 697.23 mi (1,122.08 km) |
| Opelika to Steubenville (Ohio) | 593.21 mi (954.69 km) |
| Opelika to Stevens Point (Wisconsin) | 849.76 mi (1,367.55 km) |
| Opelika to Stevenson Ranch (California) | 1,908.16 mi (3,070.89 km) |
| Opelika to Stillwater (Minnesota) | 944.71 mi (1,520.37 km) |
| Opelika to Stillwater (Oklahoma) | 708.11 mi (1,139.59 km) |
| Opelika to Stockbridge (Georgia) | 89.31 mi (143.73 km) |
| Opelika to Stockton (California) | 2,045.85 mi (3,292.48 km) |
| Opelika to Stone Ridge (Virginia) | 615.71 mi (990.89 km) |
| Opelika to Stonecrest (Georgia) | 100.68 mi (162.02 km) |
| Opelika to Stony Brook (New York) | 883.87 mi (1,422.44 km) |
