| Opelika to Yonkers (New York) | 854.85 mi (1,375.75 km) |
| Opelika to Yorba Linda (California) | 1,865.46 mi (3,002.16 km) |
| Opelika to York (Pennsylvania) | 696.69 mi (1,121.21 km) |
| Opelika to Yorktown (Indiana) | 519.76 mi (836.47 km) |
| Opelika to Yorkville (Illinois) | 644.01 mi (1,036.43 km) |
| Opelika to Youngstown (Ohio) | 638.68 mi (1,027.86 km) |
| Opelika to Youngsville (Louisiana) | 428.71 mi (689.94 km) |
| Opelika to Ypsilanti (Michigan) | 669.03 mi (1,076.70 km) |
| Opelika to Yuba City (California) | 2,063.86 mi (3,321.45 km) |
| Opelika to Yucaipa (California) | 1,822.87 mi (2,933.62 km) |
| Opelika to Yucca Valley (California) | 1,786.87 mi (2,875.69 km) |
| Opelika to Yukon (Oklahoma) | 735.20 mi (1,183.20 km) |
| Opelika to Yulee (Florida) | 264.16 mi (425.12 km) |
| Opelika to Yuma (Arizona) | 1,692.05 mi (2,723.10 km) |
| Opelika to Zachary (Louisiana) | 367.13 mi (590.84 km) |
