| Opfikon to Sacile | 212.11 mi (341.36 km) |
| Opfikon to Sala Consilina | 598.36 mi (962.97 km) |
| Opfikon to Salemi | 698.15 mi (1,123.56 km) |
| Opfikon to Salerno | 558.37 mi (898.62 km) |
| Opfikon to Salo | 157.43 mi (253.36 km) |
| Opfikon to Salsomaggiore Terme | 193.15 mi (310.84 km) |
| Opfikon to Saluzzo | 199.42 mi (320.94 km) |
| Opfikon to Salzano | 213.87 mi (344.20 km) |
| Opfikon to Samarate | 125.94 mi (202.68 km) |
| Opfikon to San Benedetto del Tronto | 403.50 mi (649.37 km) |
| Opfikon to San Biagio di Callalta | 217.70 mi (350.35 km) |
| Opfikon to San Bonifacio | 190.98 mi (307.35 km) |
| Opfikon to San Casciano in Val di Pesa | 290.03 mi (466.76 km) |
| Opfikon to San Cataldo | 740.38 mi (1,191.53 km) |
| Opfikon to San Cesareo | 440.21 mi (708.46 km) |
