| Orangeburg to Orbetello | 4,802.66 mi (7,729.13 km) |
| Orangeburg to Oria | 5,158.08 mi (8,301.13 km) |
| Orangeburg to Oristano | 4,760.26 mi (7,660.90 km) |
| Orangeburg to Orta Nova | 5,042.49 mi (8,115.11 km) |
| Orangeburg to Orte | 4,855.07 mi (7,813.48 km) |
| Orangeburg to Ortona | 4,949.09 mi (7,964.79 km) |
| Orangeburg to Orvieto | 4,834.36 mi (7,780.16 km) |
| Orangeburg to Orzinuovi | 4,654.99 mi (7,491.48 km) |
| Orangeburg to Osimo | 4,870.94 mi (7,839.02 km) |
| Orangeburg to Ospitaletto | 4,656.51 mi (7,493.93 km) |
| Orangeburg to Ostuni | 5,147.50 mi (8,284.10 km) |
| Orangeburg to Ottaviano | 5,003.13 mi (8,051.75 km) |
| Orangeburg to Ovada | 4,620.44 mi (7,435.89 km) |
| Orangeburg to Ozieri | 4,758.65 mi (7,658.30 km) |
| Orangeburg to Paceco | 5,010.38 mi (8,063.43 km) |
