| Orangeburg to Santa Venerina | 5,142.92 mi (8,276.74 km) |
| Orangeburg to Santeramo in Colle | 5,108.46 mi (8,221.27 km) |
| Orangeburg to Santo Stefano di Magra | 4,691.15 mi (7,549.67 km) |
| Orangeburg to Santo Stino di Livenza | 4,764.25 mi (7,667.33 km) |
| Orangeburg to Sarezzo | 4,659.23 mi (7,498.31 km) |
| Orangeburg to Sarno | 5,010.59 mi (8,063.77 km) |
| Orangeburg to Saronno | 4,609.08 mi (7,417.59 km) |
| Orangeburg to Sarzana | 4,694.62 mi (7,555.27 km) |
| Orangeburg to Sassari | 4,733.44 mi (7,617.74 km) |
| Orangeburg to Sasso Marconi | 4,743.17 mi (7,633.39 km) |
| Orangeburg to Sassuolo | 4,718.00 mi (7,592.88 km) |
| Orangeburg to Sava | 5,158.66 mi (8,302.06 km) |
| Orangeburg to Saviano | 5,002.65 mi (8,050.98 km) |
| Orangeburg to Savigliano | 4,574.87 mi (7,362.54 km) |
| Orangeburg to Savignano sul Panaro | 4,731.03 mi (7,613.86 km) |
