| Orangeburg to Sestu | 4,802.95 mi (7,729.60 km) |
| Orangeburg to Settimo Torinese | 4,567.08 mi (7,350.01 km) |
| Orangeburg to Seveso | 4,612.96 mi (7,423.84 km) |
| Orangeburg to Sezze | 4,917.19 mi (7,913.45 km) |
| Orangeburg to Siano | 5,014.61 mi (8,070.24 km) |
| Orangeburg to Siena | 4,780.40 mi (7,693.31 km) |
| Orangeburg to Signa | 4,755.58 mi (7,653.36 km) |
| Orangeburg to Silea | 4,750.05 mi (7,644.46 km) |
| Orangeburg to Silvi Paese | 4,929.77 mi (7,933.70 km) |
| Orangeburg to Sinalunga | 4,801.60 mi (7,727.43 km) |
| Orangeburg to Siniscola | 4,791.44 mi (7,711.07 km) |
| Orangeburg to Sinnai | 4,808.15 mi (7,737.97 km) |
| Orangeburg to Siracusa | 5,171.86 mi (8,323.30 km) |
| Orangeburg to Solaro | 4,611.44 mi (7,421.39 km) |
| Orangeburg to Soliera | 4,718.44 mi (7,593.59 km) |
