| Orbetello to Somma Lombardo | 256.48 mi (412.76 km) |
| Orbetello to Somma Vesuviana | 198.54 mi (319.52 km) |
| Orbetello to Sommacampagna | 205.35 mi (330.48 km) |
| Orbetello to Sona | 207.72 mi (334.29 km) |
| Orbetello to Sondrio | 266.14 mi (428.31 km) |
| Orbetello to Sora | 133.02 mi (214.07 km) |
| Orbetello to Sorbolo | 170.63 mi (274.60 km) |
| Orbetello to Soresina | 207.97 mi (334.70 km) |
| Orbetello to Sorisole | 240.59 mi (387.20 km) |
| Orbetello to Sorrento | 205.88 mi (331.34 km) |
| Orbetello to Sorso | 177.14 mi (285.09 km) |
| Orbetello to Sortino | 416.84 mi (670.84 km) |
| Orbetello to Soverato Marina | 381.75 mi (614.37 km) |
| Orbetello to Sovicille | 58.32 mi (93.85 km) |
| Orbetello to Spello | 83.26 mi (134.00 km) |
