| Orvieto to Santeramo in Colle | 274.10 mi (441.12 km) |
| Orvieto to Santo Stefano di Magra | 148.60 mi (239.15 km) |
| Orvieto to Santo Stino di Livenza | 210.24 mi (338.34 km) |
| Orvieto to Sarezzo | 223.57 mi (359.79 km) |
| Orvieto to Sarno | 184.23 mi (296.48 km) |
| Orvieto to Saronno | 252.04 mi (405.62 km) |
| Orvieto to Sarzana | 144.70 mi (232.87 km) |
| Orvieto to Sassari | 229.03 mi (368.59 km) |
| Orvieto to Sasso Marconi | 123.92 mi (199.43 km) |
| Orvieto to Sassuolo | 142.95 mi (230.05 km) |
| Orvieto to Sava | 324.29 mi (521.90 km) |
| Orvieto to Saviano | 175.63 mi (282.64 km) |
| Orvieto to Savigliano | 260.43 mi (419.12 km) |
| Orvieto to Savignano sul Panaro | 133.32 mi (214.56 km) |
| Orvieto to Savignano sul Rubicone | 95.70 mi (154.02 km) |
