| Paducah to Des Plaines (Illinois) | 345.21 mi (555.56 km) |
| Paducah to Desert Hot Springs (California) | 1,578.01 mi (2,539.57 km) |
| Paducah to DeSoto (Texas) | 558.89 mi (899.44 km) |
| Paducah to Destin (Florida) | 477.84 mi (769.02 km) |
| Paducah to Destrehan (Louisiana) | 501.06 mi (806.37 km) |
| Paducah to Detroit (Michigan) | 470.34 mi (756.94 km) |
| Paducah to Diamond Bar (California) | 1,647.36 mi (2,651.17 km) |
| Paducah to Diamond Springs (California) | 1,750.28 mi (2,816.81 km) |
| Paducah to Dickinson (North Dakota) | 991.39 mi (1,595.48 km) |
| Paducah to Dickinson (Texas) | 643.25 mi (1,035.21 km) |
| Paducah to Dickson (Tennessee) | 99.35 mi (159.89 km) |
| Paducah to Difficult Run (Virginia) | 627.61 mi (1,010.04 km) |
| Paducah to Dinuba (California) | 1,694.24 mi (2,726.62 km) |
| Paducah to Discovery Bay (California) | 1,798.19 mi (2,893.91 km) |
| Paducah to Dix Hills (New York) | 860.75 mi (1,385.25 km) |
