| Paducah to Olympia (Washington) | 1,869.08 mi (3,008.00 km) |
| Paducah to Olympia Heights (Florida) | 923.47 mi (1,486.19 km) |
| Paducah to Omaha (Nebraska) | 491.01 mi (790.21 km) |
| Paducah to On Top of the World Designated Place (Florida) | 661.65 mi (1,064.83 km) |
| Paducah to Onalaska (Wisconsin) | 489.84 mi (788.32 km) |
| Paducah to Oneida (New York) | 800.69 mi (1,288.58 km) |
| Paducah to Oneonta (New York) | 810.07 mi (1,303.69 km) |
| Paducah to Ontario (California) | 1,635.05 mi (2,631.36 km) |
| Paducah to Ontario (Oregon) | 1,554.18 mi (2,501.22 km) |
| Paducah to Opa-locka (Florida) | 915.60 mi (1,473.52 km) |
| Paducah to Opelika (Alabama) | 356.51 mi (573.74 km) |
| Paducah to Opelousas (Louisiana) | 493.37 mi (793.99 km) |
| Paducah to Orange (California) | 1,651.40 mi (2,657.67 km) |
| Paducah to Orange (Texas) | 562.97 mi (906.02 km) |
| Paducah to Orange City (Florida) | 704.94 mi (1,134.49 km) |
