| Paducah to Orangeburg (South Carolina) | 503.26 mi (809.92 km) |
| Paducah to Orangevale (California) | 1,770.77 mi (2,849.77 km) |
| Paducah to Orchards (Washington) | 1,838.92 mi (2,959.46 km) |
| Paducah to Orcutt (California) | 1,775.24 mi (2,856.97 km) |
| Paducah to Oregon (Ohio) | 421.39 mi (678.16 km) |
| Paducah to Oregon (Wisconsin) | 406.40 mi (654.04 km) |
| Paducah to Oregon City (Oregon) | 1,839.22 mi (2,959.93 km) |
| Paducah to Orem (Utah) | 1,259.57 mi (2,027.09 km) |
| Paducah to Orinda (California) | 1,829.73 mi (2,944.66 km) |
| Paducah to Orland Park (Illinois) | 316.20 mi (508.88 km) |
| Paducah to Orlando (Florida) | 729.34 mi (1,173.76 km) |
| Paducah to Ormond Beach (Florida) | 691.29 mi (1,112.53 km) |
| Paducah to Oro Valley (Arizona) | 1,304.60 mi (2,099.54 km) |
| Paducah to Oroville (California) | 1,783.26 mi (2,869.88 km) |
| Paducah to Oshkosh (Wisconsin) | 480.33 mi (773.01 km) |
