| Paducah to Security-Widefield (Colorado) | 882.50 mi (1,420.25 km) |
| Paducah to Sedalia (Missouri) | 274.55 mi (441.85 km) |
| Paducah to Sedro-Woolley (Washington) | 1,857.90 mi (2,990.00 km) |
| Paducah to Seguin (Texas) | 745.52 mi (1,199.80 km) |
| Paducah to Selden (New York) | 876.62 mi (1,410.78 km) |
| Paducah to Selma (Alabama) | 334.32 mi (538.04 km) |
| Paducah to Selma (California) | 1,705.67 mi (2,745.02 km) |
| Paducah to Selma (Texas) | 760.11 mi (1,223.28 km) |
| Paducah to Seminole (Florida) | 722.92 mi (1,163.43 km) |
| Paducah to Seven Hills (Ohio) | 477.05 mi (767.73 km) |
| Paducah to Seven Oaks (South Carolina) | 470.31 mi (756.89 km) |
| Paducah to Severn (Maryland) | 664.57 mi (1,069.52 km) |
| Paducah to Severna Park (Maryland) | 670.81 mi (1,079.56 km) |
| Paducah to Sevierville (Tennessee) | 293.59 mi (472.49 km) |
| Paducah to Seymour (Indiana) | 198.15 mi (318.89 km) |
