| Paducah to St. Simons (Georgia) | 581.15 mi (935.27 km) |
| Paducah to Stafford (Texas) | 650.80 mi (1,047.36 km) |
| Paducah to Stallings (North Carolina) | 465.78 mi (749.59 km) |
| Paducah to Stamford (Connecticut) | 854.31 mi (1,374.88 km) |
| Paducah to Stanford (California) | 1,834.10 mi (2,951.70 km) |
| Paducah to Stanton (California) | 1,660.93 mi (2,673.01 km) |
| Paducah to Star (Idaho) | 1,527.15 mi (2,457.72 km) |
| Paducah to Starkville (Mississippi) | 249.67 mi (401.80 km) |
| Paducah to State College (Pennsylvania) | 633.62 mi (1,019.71 km) |
| Paducah to Staten Island (New York) | 815.93 mi (1,313.11 km) |
| Paducah to Statesboro (Georgia) | 504.26 mi (811.53 km) |
| Paducah to Statesville (North Carolina) | 441.02 mi (709.76 km) |
| Paducah to Staunton (Virginia) | 529.59 mi (852.30 km) |
| Paducah to Steamboat Springs (Colorado) | 1,005.21 mi (1,617.72 km) |
| Paducah to Steiner Ranch (Texas) | 704.59 mi (1,133.92 km) |
