| Paducah to University Place (Washington) | 1,854.82 mi (2,985.04 km) |
| Paducah to Upland (California) | 1,636.56 mi (2,633.79 km) |
| Paducah to Upper Arlington (Ohio) | 363.78 mi (585.45 km) |
| Paducah to Upper Grand Lagoon (Florida) | 505.22 mi (813.07 km) |
| Paducah to Upper Montclair (New Jersey) | 817.45 mi (1,315.56 km) |
| Paducah to Urbana (Illinois) | 211.40 mi (340.21 km) |
| Paducah to Urbana (Maryland) | 632.67 mi (1,018.19 km) |
| Paducah to Urbana (Ohio) | 337.22 mi (542.70 km) |
| Paducah to Urbandale (Iowa) | 418.09 mi (672.84 km) |
| Paducah to Utica (New York) | 820.99 mi (1,321.26 km) |
| Paducah to Uvalde (Texas) | 841.23 mi (1,353.82 km) |
| Paducah to Vacaville (California) | 1,813.64 mi (2,918.77 km) |
| Paducah to Vadnais Heights (Minnesota) | 597.86 mi (962.16 km) |
| Paducah to Vail (Arizona) | 1,299.07 mi (2,090.65 km) |
| Paducah to Valdosta (Georgia) | 528.24 mi (850.13 km) |
