| Painesville to Enterprise (Nevada) | 1,857.16 mi (2,988.81 km) |
| Painesville to Enumclaw (Washington) | 2,020.32 mi (3,251.39 km) |
| Painesville to Ephrata (Pennsylvania) | 285.29 mi (459.14 km) |
| Painesville to Erie (Colorado) | 1,244.01 mi (2,002.04 km) |
| Painesville to Erie (Pennsylvania) | 66.47 mi (106.97 km) |
| Painesville to Erlanger (Kentucky) | 256.71 mi (413.13 km) |
| Painesville to Escanaba (Michigan) | 402.52 mi (647.79 km) |
| Painesville to Escondido (California) | 2,036.43 mi (3,277.33 km) |
| Painesville to Española (New Mexico) | 1,386.72 mi (2,231.71 km) |
| Painesville to Essex (Maryland) | 302.92 mi (487.50 km) |
| Painesville to Essex Junction (Vermont) | 452.61 mi (728.41 km) |
| Painesville to Estelle (Louisiana) | 957.72 mi (1,541.30 km) |
| Painesville to Estero (Florida) | 1,057.33 mi (1,701.60 km) |
| Painesville to Euclid (Ohio) | 16.52 mi (26.58 km) |
| Painesville to Eufaula (Alabama) | 711.28 mi (1,144.70 km) |
