| Palermo to Sangeorz-Bai | 857.71 mi (1,380.34 km) |
| Palermo to Sannicolau Mare | 662.53 mi (1,066.24 km) |
| Palermo to Santana | 704.18 mi (1,133.27 km) |
| Palermo to Satu Mare | 822.65 mi (1,323.93 km) |
| Palermo to Scobinti | 937.81 mi (1,509.26 km) |
| Palermo to Scornicesti | 730.80 mi (1,176.12 km) |
| Palermo to Sebes | 752.59 mi (1,211.17 km) |
| Palermo to Seini | 832.17 mi (1,339.26 km) |
| Palermo to Sfantu-Gheorghe | 831.24 mi (1,337.75 km) |
| Palermo to Sibiu | 766.03 mi (1,232.80 km) |
| Palermo to Sighetu Marmatiei | 860.12 mi (1,384.23 km) |
| Palermo to Sighisoara | 808.36 mi (1,300.93 km) |
| Palermo to Simeria | 727.74 mi (1,171.19 km) |
| Palermo to Sinaia | 801.54 mi (1,289.95 km) |
| Palermo to Slatina | 717.81 mi (1,155.20 km) |
