| Palermo to Santander | 968.72 mi (1,559.00 km) |
| Palermo to Santany | 557.80 mi (897.70 km) |
| Palermo to Santiago de Compostela | 1,193.18 mi (1,920.24 km) |
| Palermo to Santiago del Teide | 1,861.47 mi (2,995.74 km) |
| Palermo to Santiponce | 1,058.85 mi (1,704.05 km) |
| Palermo to Santomera | 782.87 mi (1,259.90 km) |
| Palermo to Santona | 951.61 mi (1,531.46 km) |
| Palermo to Santurce-Antiguo | 928.90 mi (1,494.92 km) |
| Palermo to Sarria | 1,135.73 mi (1,827.77 km) |
| Palermo to Sauzal | 1,835.16 mi (2,953.40 km) |
| Palermo to Sedavi | 745.27 mi (1,199.40 km) |
| Palermo to Segorbe | 752.72 mi (1,211.38 km) |
| Palermo to Segovia | 950.09 mi (1,529.03 km) |
| Palermo to Senmanat | 641.78 mi (1,032.84 km) |
| Palermo to Sesena | 923.38 mi (1,486.03 km) |
