| Palma del Rio to Sestu | 784.27 mi (1,262.15 km) |
| Palma del Rio to Settimo Torinese | 847.34 mi (1,363.66 km) |
| Palma del Rio to Seveso | 922.41 mi (1,484.48 km) |
| Palma del Rio to Sezze | 1,009.40 mi (1,624.46 km) |
| Palma del Rio to Siano | 1,087.65 mi (1,750.41 km) |
| Palma del Rio to Siena | 953.03 mi (1,533.75 km) |
| Palma del Rio to Signa | 952.82 mi (1,533.41 km) |
| Palma del Rio to Silea | 1,057.27 mi (1,701.50 km) |
| Palma del Rio to Silvi Paese | 1,075.46 mi (1,730.79 km) |
| Palma del Rio to Sinalunga | 970.12 mi (1,561.25 km) |
| Palma del Rio to Siniscola | 825.84 mi (1,329.07 km) |
| Palma del Rio to Sinnai | 790.22 mi (1,271.74 km) |
| Palma del Rio to Siracusa | 1,127.91 mi (1,815.20 km) |
| Palma del Rio to Solaro | 919.18 mi (1,479.28 km) |
| Palma del Rio to Soliera | 970.06 mi (1,561.16 km) |
