| Palma del Rio to Spello | 1,011.19 mi (1,627.35 km) |
| Palma del Rio to Spilamberto | 968.45 mi (1,558.56 km) |
| Palma del Rio to Spilimbergo | 1,096.84 mi (1,765.19 km) |
| Palma del Rio to Spinea | 1,046.59 mi (1,684.32 km) |
| Palma del Rio to Spoleto | 1,007.77 mi (1,621.85 km) |
| Palma del Rio to Spoltore | 1,075.32 mi (1,730.56 km) |
| Palma del Rio to Spresiano | 1,059.04 mi (1,704.35 km) |
| Palma del Rio to Squinzano | 1,262.10 mi (2,031.16 km) |
| Palma del Rio to Statte | 1,217.71 mi (1,959.71 km) |
| Palma del Rio to Stezzano | 944.04 mi (1,519.29 km) |
| Palma del Rio to Strada | 958.27 mi (1,542.18 km) |
| Palma del Rio to Stradella | 909.76 mi (1,464.11 km) |
| Palma del Rio to Striano | 1,081.08 mi (1,739.84 km) |
| Palma del Rio to Subiaco | 1,016.20 mi (1,635.42 km) |
| Palma del Rio to Sulmona | 1,059.36 mi (1,704.88 km) |
