| Palos de la Frontera to Orbetello | 1,023.45 mi (1,647.08 km) |
| Palos de la Frontera to Oria | 1,334.30 mi (2,147.35 km) |
| Palos de la Frontera to Oristano | 855.62 mi (1,376.98 km) |
| Palos de la Frontera to Orta Nova | 1,237.96 mi (1,992.30 km) |
| Palos de la Frontera to Orte | 1,081.90 mi (1,741.15 km) |
| Palos de la Frontera to Ortona | 1,180.97 mi (1,900.59 km) |
| Palos de la Frontera to Orvieto | 1,072.49 mi (1,726.00 km) |
| Palos de la Frontera to Orzinuovi | 1,036.69 mi (1,668.39 km) |
| Palos de la Frontera to Osimo | 1,152.91 mi (1,855.43 km) |
| Palos de la Frontera to Ospitaletto | 1,047.63 mi (1,686.00 km) |
| Palos de la Frontera to Ostuni | 1,332.29 mi (2,144.11 km) |
| Palos de la Frontera to Ottaviano | 1,170.77 mi (1,884.17 km) |
| Palos de la Frontera to Ovada | 956.82 mi (1,539.85 km) |
| Palos de la Frontera to Ozieri | 884.27 mi (1,423.09 km) |
| Palos de la Frontera to Paceco | 1,063.68 mi (1,711.83 km) |
