| Palos de la Frontera to Santa Venerina | 1,205.80 mi (1,940.54 km) |
| Palos de la Frontera to Santeramo in Colle | 1,289.85 mi (2,075.81 km) |
| Palos de la Frontera to Santo Stefano di Magra | 999.77 mi (1,608.97 km) |
| Palos de la Frontera to Santo Stino di Livenza | 1,166.87 mi (1,877.90 km) |
| Palos de la Frontera to Sarezzo | 1,056.08 mi (1,699.59 km) |
| Palos de la Frontera to Sarno | 1,177.80 mi (1,895.49 km) |
| Palos de la Frontera to Saronno | 1,005.89 mi (1,618.82 km) |
| Palos de la Frontera to Sarzana | 1,000.52 mi (1,610.17 km) |
| Palos de la Frontera to Sassari | 863.21 mi (1,389.19 km) |
| Palos de la Frontera to Sasso Marconi | 1,067.12 mi (1,717.36 km) |
| Palos de la Frontera to Sassuolo | 1,049.83 mi (1,689.53 km) |
| Palos de la Frontera to Sava | 1,330.60 mi (2,141.39 km) |
| Palos de la Frontera to Saviano | 1,173.25 mi (1,888.16 km) |
| Palos de la Frontera to Savigliano | 913.21 mi (1,469.67 km) |
| Palos de la Frontera to Savignano sul Panaro | 1,059.32 mi (1,704.80 km) |
