| Palos de la Frontera to Selargius | 881.21 mi (1,418.17 km) |
| Palos de la Frontera to Selvazzano Dentro | 1,117.30 mi (1,798.12 km) |
| Palos de la Frontera to Senago | 1,008.51 mi (1,623.04 km) |
| Palos de la Frontera to Senigallia | 1,144.41 mi (1,841.76 km) |
| Palos de la Frontera to Seravezza | 1,010.12 mi (1,625.64 km) |
| Palos de la Frontera to Seregno | 1,013.58 mi (1,631.20 km) |
| Palos de la Frontera to Seriate | 1,036.63 mi (1,668.29 km) |
| Palos de la Frontera to Sermoneta | 1,099.84 mi (1,770.02 km) |
| Palos de la Frontera to Serramanna | 869.41 mi (1,399.18 km) |
| Palos de la Frontera to Serravalle Pistoiese | 1,035.50 mi (1,666.48 km) |
| Palos de la Frontera to Sessa Aurunca | 1,145.47 mi (1,843.45 km) |
| Palos de la Frontera to Sesto Calende | 992.79 mi (1,597.75 km) |
| Palos de la Frontera to Sesto Fiorentino | 1,051.10 mi (1,691.58 km) |
| Palos de la Frontera to Sesto San Giovanni | 1,011.06 mi (1,627.14 km) |
| Palos de la Frontera to Sestri Levante | 979.13 mi (1,575.75 km) |
