| Palos de la Frontera to Spello | 1,104.71 mi (1,777.86 km) |
| Palos de la Frontera to Spilamberto | 1,059.86 mi (1,705.68 km) |
| Palos de la Frontera to Spilimbergo | 1,186.72 mi (1,909.84 km) |
| Palos de la Frontera to Spinea | 1,137.10 mi (1,829.98 km) |
| Palos de la Frontera to Spoleto | 1,101.45 mi (1,772.61 km) |
| Palos de la Frontera to Spoltore | 1,169.27 mi (1,881.75 km) |
| Palos de la Frontera to Spresiano | 1,149.14 mi (1,849.36 km) |
| Palos de la Frontera to Squinzano | 1,356.07 mi (2,182.39 km) |
| Palos de la Frontera to Statte | 1,311.73 mi (2,111.02 km) |
| Palos de la Frontera to Stezzano | 1,032.75 mi (1,662.05 km) |
| Palos de la Frontera to Strada | 1,050.98 mi (1,691.40 km) |
| Palos de la Frontera to Stradella | 999.29 mi (1,608.20 km) |
| Palos de la Frontera to Striano | 1,175.20 mi (1,891.30 km) |
| Palos de la Frontera to Subiaco | 1,110.28 mi (1,786.82 km) |
| Palos de la Frontera to Sulmona | 1,153.44 mi (1,856.28 km) |
