| Palos de la Frontera to Ede | 1,192.04 mi (1,918.40 km) |
| Palos de la Frontera to Eemnes | 1,193.21 mi (1,920.29 km) |
| Palos de la Frontera to Eerbeek | 1,205.06 mi (1,939.36 km) |
| Palos de la Frontera to Eersel | 1,144.09 mi (1,841.24 km) |
| Palos de la Frontera to Eijsden | 1,122.94 mi (1,807.20 km) |
| Palos de la Frontera to Eindhoven | 1,152.99 mi (1,855.55 km) |
| Palos de la Frontera to Elburg | 1,219.03 mi (1,961.84 km) |
| Palos de la Frontera to Emmeloord | 1,231.33 mi (1,981.63 km) |
| Palos de la Frontera to Emmen | 1,263.68 mi (2,033.69 km) |
| Palos de la Frontera to Enkhuizen | 1,220.16 mi (1,963.66 km) |
| Palos de la Frontera to Enschede | 1,232.73 mi (1,983.88 km) |
| Palos de la Frontera to Epe | 1,216.69 mi (1,958.08 km) |
| Palos de la Frontera to Ermelo | 1,204.89 mi (1,939.08 km) |
| Palos de la Frontera to Etten-Leur | 1,139.39 mi (1,833.67 km) |
| Palos de la Frontera to Franeker | 1,254.33 mi (2,018.65 km) |
