| Palos de la Frontera to Sangeorgiu de Mures | 1,722.77 mi (2,772.53 km) |
| Palos de la Frontera to Sangeorz-Bai | 1,743.78 mi (2,806.34 km) |
| Palos de la Frontera to Sannicolau Mare | 1,535.87 mi (2,471.74 km) |
| Palos de la Frontera to Santana | 1,581.74 mi (2,545.56 km) |
| Palos de la Frontera to Satu Mare | 1,669.43 mi (2,686.69 km) |
| Palos de la Frontera to Scobinti | 1,847.45 mi (2,973.18 km) |
| Palos de la Frontera to Scornicesti | 1,706.66 mi (2,746.61 km) |
| Palos de la Frontera to Sebes | 1,673.26 mi (2,692.86 km) |
| Palos de la Frontera to Seini | 1,686.45 mi (2,714.09 km) |
| Palos de la Frontera to Sfantu-Gheorghe | 1,777.49 mi (2,860.59 km) |
| Palos de la Frontera to Sibiu | 1,698.89 mi (2,734.11 km) |
| Palos de la Frontera to Sighetu Marmatiei | 1,716.82 mi (2,762.96 km) |
| Palos de la Frontera to Sighisoara | 1,733.96 mi (2,790.54 km) |
| Palos de la Frontera to Simeria | 1,645.41 mi (2,648.04 km) |
| Palos de la Frontera to Sinaia | 1,761.55 mi (2,834.94 km) |
