| Penafiel to Orbetello | 1,005.24 mi (1,617.79 km) |
| Penafiel to Oria | 1,350.34 mi (2,173.16 km) |
| Penafiel to Oristano | 889.02 mi (1,430.73 km) |
| Penafiel to Orta Nova | 1,242.17 mi (1,999.08 km) |
| Penafiel to Orte | 1,064.99 mi (1,713.93 km) |
| Penafiel to Ortona | 1,167.99 mi (1,879.70 km) |
| Penafiel to Orvieto | 1,050.41 mi (1,690.47 km) |
| Penafiel to Orzinuovi | 958.29 mi (1,542.21 km) |
| Penafiel to Osimo | 1,119.40 mi (1,801.50 km) |
| Penafiel to Ospitaletto | 967.05 mi (1,556.31 km) |
| Penafiel to Ostuni | 1,344.89 mi (2,164.39 km) |
| Penafiel to Ottaviano | 1,183.26 mi (1,904.28 km) |
| Penafiel to Ovada | 886.99 mi (1,427.48 km) |
| Penafiel to Ozieri | 902.41 mi (1,452.29 km) |
| Penafiel to Paceco | 1,128.47 mi (1,816.10 km) |
