| Penafiel to Santa Venerina | 1,268.89 mi (2,042.08 km) |
| Penafiel to Santeramo in Colle | 1,301.99 mi (2,095.35 km) |
| Penafiel to Santo Stefano di Magra | 944.54 mi (1,520.08 km) |
| Penafiel to Santo Stino di Livenza | 1,093.28 mi (1,759.46 km) |
| Penafiel to Sarezzo | 974.37 mi (1,568.10 km) |
| Penafiel to Sarno | 1,190.81 mi (1,916.42 km) |
| Penafiel to Saronno | 919.15 mi (1,479.23 km) |
| Penafiel to Sarzana | 946.40 mi (1,523.08 km) |
| Penafiel to Sassari | 877.99 mi (1,412.99 km) |
| Penafiel to Sasso Marconi | 1,011.92 mi (1,628.52 km) |
| Penafiel to Sassuolo | 990.31 mi (1,593.74 km) |
| Penafiel to Sava | 1,348.18 mi (2,169.68 km) |
| Penafiel to Saviano | 1,184.60 mi (1,906.43 km) |
| Penafiel to Savigliano | 838.12 mi (1,348.82 km) |
| Penafiel to Savignano sul Panaro | 1,001.89 mi (1,612.39 km) |
