| Penafiel to Spello | 1,078.57 mi (1,735.80 km) |
| Penafiel to Spilamberto | 1,001.46 mi (1,611.70 km) |
| Penafiel to Spilimbergo | 1,107.43 mi (1,782.23 km) |
| Penafiel to Spinea | 1,065.73 mi (1,715.12 km) |
| Penafiel to Spoleto | 1,079.53 mi (1,737.34 km) |
| Penafiel to Spoltore | 1,154.30 mi (1,857.66 km) |
| Penafiel to Spresiano | 1,073.24 mi (1,727.21 km) |
| Penafiel to Squinzano | 1,372.72 mi (2,209.17 km) |
| Penafiel to Statte | 1,327.12 mi (2,135.80 km) |
| Penafiel to Stezzano | 948.54 mi (1,526.53 km) |
| Penafiel to Strada | 1,011.11 mi (1,627.22 km) |
| Penafiel to Stradella | 923.90 mi (1,486.87 km) |
| Penafiel to Striano | 1,188.22 mi (1,912.26 km) |
| Penafiel to Subiaco | 1,103.66 mi (1,776.17 km) |
| Penafiel to Sulmona | 1,145.32 mi (1,843.22 km) |
