| Penafiel to Schiedam | 951.51 mi (1,531.31 km) |
| Penafiel to Schijndel | 968.65 mi (1,558.89 km) |
| Penafiel to Schinnen | 953.10 mi (1,533.86 km) |
| Penafiel to Schoonhoven | 966.58 mi (1,555.56 km) |
| Penafiel to Simpelveld | 951.39 mi (1,531.11 km) |
| Penafiel to Sint Anthonis | 983.34 mi (1,582.53 km) |
| Penafiel to Sint Willebrord | 939.29 mi (1,511.65 km) |
| Penafiel to Sint-Michielsgestel | 967.54 mi (1,557.11 km) |
| Penafiel to Sint-Oedenrode | 967.04 mi (1,556.31 km) |
| Penafiel to Sittard | 954.74 mi (1,536.50 km) |
| Penafiel to Sliedrecht | 957.56 mi (1,541.05 km) |
| Penafiel to Slochteren | 1,086.30 mi (1,748.22 km) |
| Penafiel to Sluis | 891.08 mi (1,434.05 km) |
| Penafiel to Sneek | 1,043.80 mi (1,679.83 km) |
| Penafiel to Soest | 991.50 mi (1,595.67 km) |
