| Penafiel to Santiago do Cacem | 221.47 mi (356.42 km) |
| Penafiel to Santo Andre | 219.46 mi (353.19 km) |
| Penafiel to Santo Tirso | 12.94 mi (20.82 km) |
| Penafiel to Sao Bras de Alportel | 281.06 mi (452.33 km) |
| Penafiel to Sao Felix da Marinha | 21.27 mi (34.24 km) |
| Penafiel to Sao Joao da Madeira | 23.86 mi (38.40 km) |
| Penafiel to Sao Joao de Ver | 22.28 mi (35.86 km) |
| Penafiel to Sao Mamede de Infesta | 16.43 mi (26.45 km) |
| Penafiel to Sao Pedro do Sul | 33.48 mi (53.89 km) |
| Penafiel to Satao | 43.50 mi (70.00 km) |
| Penafiel to Seia | 62.12 mi (99.98 km) |
| Penafiel to Senhora da Hora | 19.13 mi (30.79 km) |
| Penafiel to Serpa | 228.27 mi (367.36 km) |
| Penafiel to Serta | 97.62 mi (157.11 km) |
| Penafiel to Sesimbra | 195.70 mi (314.95 km) |
