| Penafiel to Sangeorz-Bai | 1,671.38 mi (2,689.83 km) |
| Penafiel to Sannicolau Mare | 1,474.71 mi (2,373.32 km) |
| Penafiel to Santana | 1,518.04 mi (2,443.05 km) |
| Penafiel to Satu Mare | 1,590.05 mi (2,558.94 km) |
| Penafiel to Scobinti | 1,776.79 mi (2,859.47 km) |
| Penafiel to Scornicesti | 1,666.90 mi (2,682.61 km) |
| Penafiel to Sebes | 1,616.40 mi (2,601.34 km) |
| Penafiel to Seini | 1,608.10 mi (2,587.99 km) |
| Penafiel to Sfantu-Gheorghe | 1,723.07 mi (2,773.01 km) |
| Penafiel to Sibiu | 1,644.43 mi (2,646.45 km) |
| Penafiel to Sighetu Marmatiei | 1,637.16 mi (2,634.75 km) |
| Penafiel to Sighisoara | 1,674.93 mi (2,695.54 km) |
| Penafiel to Simeria | 1,589.43 mi (2,557.95 km) |
| Penafiel to Sinaia | 1,712.92 mi (2,756.68 km) |
| Penafiel to Slatina | 1,658.39 mi (2,668.92 km) |
