| Penzance to Sacile | 878.59 mi (1,413.96 km) |
| Penzance to Sala Consilina | 1,221.21 mi (1,965.34 km) |
| Penzance to Salemi | 1,240.34 mi (1,996.14 km) |
| Penzance to Salerno | 1,175.05 mi (1,891.06 km) |
| Penzance to Salo | 805.70 mi (1,296.65 km) |
| Penzance to Salsomaggiore Terme | 810.01 mi (1,303.59 km) |
| Penzance to Saluzzo | 715.78 mi (1,151.94 km) |
| Penzance to Salzano | 875.46 mi (1,408.92 km) |
| Penzance to Samarate | 731.45 mi (1,177.16 km) |
| Penzance to San Benedetto del Tronto | 1,043.19 mi (1,678.86 km) |
| Penzance to San Biagio di Callalta | 882.01 mi (1,419.46 km) |
| Penzance to San Bonifacio | 844.20 mi (1,358.61 km) |
| Penzance to San Casciano in Val di Pesa | 904.22 mi (1,455.21 km) |
| Penzance to San Cataldo | 1,300.35 mi (2,092.70 km) |
| Penzance to San Cesareo | 1,046.61 mi (1,684.36 km) |
