| Penzance to Sestu | 1,033.15 mi (1,662.70 km) |
| Penzance to Settimo Torinese | 707.39 mi (1,138.43 km) |
| Penzance to Seveso | 745.34 mi (1,199.50 km) |
| Penzance to Sezze | 1,071.19 mi (1,723.92 km) |
| Penzance to Siano | 1,166.99 mi (1,878.09 km) |
| Penzance to Siena | 923.86 mi (1,486.81 km) |
| Penzance to Signa | 895.68 mi (1,441.46 km) |
| Penzance to Silea | 879.36 mi (1,415.19 km) |
| Penzance to Silvi Paese | 1,068.90 mi (1,720.23 km) |
| Penzance to Sinalunga | 944.30 mi (1,519.71 km) |
| Penzance to Siniscola | 987.58 mi (1,589.35 km) |
| Penzance to Sinnai | 1,036.72 mi (1,668.44 km) |
| Penzance to Siracusa | 1,369.55 mi (2,204.07 km) |
| Penzance to Solaro | 744.07 mi (1,197.47 km) |
| Penzance to Soliera | 852.10 mi (1,371.33 km) |
