| Philadelphia to Elyria (Ohio) | 377.17 mi (607.00 km) |
| Philadelphia to Emeryville (California) | 2,509.69 mi (4,038.96 km) |
| Philadelphia to Emmaus (Pennsylvania) | 41.19 mi (66.28 km) |
| Philadelphia to Emporia (Kansas) | 1,130.29 mi (1,819.03 km) |
| Philadelphia to Encinitas (California) | 2,365.16 mi (3,806.37 km) |
| Philadelphia to Endicott (New York) | 152.33 mi (245.16 km) |
| Philadelphia to Endwell (New York) | 152.99 mi (246.22 km) |
| Philadelphia to Englewood (Colorado) | 1,577.18 mi (2,538.22 km) |
| Philadelphia to Englewood (Florida) | 991.20 mi (1,595.18 km) |
| Philadelphia to Englewood (New Jersey) | 86.33 mi (138.93 km) |
| Philadelphia to Englewood (Ohio) | 485.86 mi (781.92 km) |
| Philadelphia to Enid (Oklahoma) | 1,255.59 mi (2,020.67 km) |
| Philadelphia to Ennis (Texas) | 1,307.10 mi (2,103.58 km) |
| Philadelphia to Ensley (Florida) | 945.99 mi (1,522.43 km) |
| Philadelphia to Enterprise (Alabama) | 848.03 mi (1,364.76 km) |
