| Philadelphia to Orangeburg (South Carolina) | 550.49 mi (885.93 km) |
| Philadelphia to Orangevale (California) | 2,436.34 mi (3,920.91 km) |
| Philadelphia to Orchards (Washington) | 2,397.01 mi (3,857.62 km) |
| Philadelphia to Orcutt (California) | 2,482.93 mi (3,995.89 km) |
| Philadelphia to Oregon (Ohio) | 448.26 mi (721.40 km) |
| Philadelphia to Oregon (Wisconsin) | 764.03 mi (1,229.59 km) |
| Philadelphia to Oregon City (Oregon) | 2,403.38 mi (3,867.86 km) |
| Philadelphia to Orem (Utah) | 1,917.19 mi (3,085.42 km) |
| Philadelphia to Orinda (California) | 2,502.85 mi (4,027.95 km) |
| Philadelphia to Orland Park (Illinois) | 674.11 mi (1,084.87 km) |
| Philadelphia to Orlando (Florida) | 871.30 mi (1,402.22 km) |
| Philadelphia to Ormond Beach (Florida) | 813.44 mi (1,309.11 km) |
| Philadelphia to Oro Valley (Arizona) | 2,050.70 mi (3,300.29 km) |
| Philadelphia to Oroville (California) | 2,437.91 mi (3,923.44 km) |
| Philadelphia to Oshkosh (Wisconsin) | 741.93 mi (1,194.03 km) |
