| Philadelphia to San Diego (California) | 2,363.99 mi (3,804.47 km) |
| Philadelphia to San Diego Country Estates (California) | 2,341.23 mi (3,767.85 km) |
| Philadelphia to San Dimas (California) | 2,365.15 mi (3,806.34 km) |
| Philadelphia to San Fernando (California) | 2,393.47 mi (3,851.92 km) |
| Philadelphia to San Francisco (California) | 2,519.36 mi (4,054.51 km) |
| Philadelphia to San Gabriel (California) | 2,380.81 mi (3,831.55 km) |
| Philadelphia to San Germán (Puerto Rico) | 1,589.89 mi (2,558.69 km) |
| Philadelphia to San Jacinto (California) | 2,330.30 mi (3,750.26 km) |
| Philadelphia to San Jose (California) | 2,498.58 mi (4,021.07 km) |
| Philadelphia to San Juan (Puerto Rico) | 1,587.94 mi (2,555.54 km) |
| Philadelphia to San Juan (Texas) | 1,630.84 mi (2,624.59 km) |
| Philadelphia to San Juan Capistrano (California) | 2,373.41 mi (3,819.63 km) |
| Philadelphia to San Leandro (California) | 2,505.67 mi (4,032.49 km) |
| Philadelphia to San Lorenzo (California) | 2,505.04 mi (4,031.48 km) |
| Philadelphia to San Luis (Arizona) | 2,246.04 mi (3,614.65 km) |
