| Philadelphia to San Luis Obispo (California) | 2,485.73 mi (4,000.39 km) |
| Philadelphia to San Marcos (California) | 2,358.17 mi (3,795.11 km) |
| Philadelphia to San Marcos (Texas) | 1,462.92 mi (2,354.35 km) |
| Philadelphia to San Marino (California) | 2,380.83 mi (3,831.58 km) |
| Philadelphia to San Mateo (California) | 2,517.01 mi (4,050.74 km) |
| Philadelphia to San Pablo (California) | 2,509.52 mi (4,038.68 km) |
| Philadelphia to San Rafael (California) | 2,518.19 mi (4,052.64 km) |
| Philadelphia to San Ramon (California) | 2,492.89 mi (4,011.92 km) |
| Philadelphia to San Tan Valley (Arizona) | 2,060.03 mi (3,315.30 km) |
| Philadelphia to Sand Springs (Oklahoma) | 1,169.89 mi (1,882.76 km) |
| Philadelphia to Sandusky (Ohio) | 408.42 mi (657.29 km) |
| Philadelphia to Sandy (Oregon) | 2,387.31 mi (3,842.00 km) |
| Philadelphia to Sandy (Utah) | 1,921.32 mi (3,092.07 km) |
| Philadelphia to Sandy Springs (Georgia) | 659.58 mi (1,061.49 km) |
| Philadelphia to Sanford (Florida) | 849.97 mi (1,367.89 km) |
