| Philadelphia to Sanford (Maine) | 326.52 mi (525.49 km) |
| Philadelphia to Sanford (North Carolina) | 382.43 mi (615.46 km) |
| Philadelphia to Sanger (California) | 2,392.95 mi (3,851.07 km) |
| Philadelphia to Santa Ana (California) | 2,378.98 mi (3,828.61 km) |
| Philadelphia to Santa Barbara (California) | 2,457.48 mi (3,954.93 km) |
| Philadelphia to Santa Clara (California) | 2,503.38 mi (4,028.80 km) |
| Philadelphia to Santa Clara (Oregon) | 2,443.50 mi (3,932.44 km) |
| Philadelphia to Santa Clarita (California) | 2,393.26 mi (3,851.58 km) |
| Philadelphia to Santa Cruz (California) | 2,515.65 mi (4,048.55 km) |
| Philadelphia to Santa Fe (New Mexico) | 1,701.12 mi (2,737.69 km) |
| Philadelphia to Santa Fe (Texas) | 1,345.91 mi (2,166.03 km) |
| Philadelphia to Santa Fe Springs (California) | 2,383.22 mi (3,835.43 km) |
| Philadelphia to Santa Maria (California) | 2,482.37 mi (3,994.99 km) |
| Philadelphia to Santa Monica (California) | 2,402.89 mi (3,867.07 km) |
| Philadelphia to Santa Paula (California) | 2,424.93 mi (3,902.55 km) |
