| Philadelphia to Santa Rosa (California) | 2,517.93 mi (4,052.21 km) |
| Philadelphia to Santaquin (Utah) | 1,926.70 mi (3,100.73 km) |
| Philadelphia to Santee (California) | 2,356.05 mi (3,791.69 km) |
| Philadelphia to Sapulpa (Oklahoma) | 1,171.37 mi (1,885.13 km) |
| Philadelphia to Saraland (Alabama) | 964.28 mi (1,551.86 km) |
| Philadelphia to Sarasota (Florida) | 972.59 mi (1,565.23 km) |
| Philadelphia to Sarasota Springs (Florida) | 972.78 mi (1,565.54 km) |
| Philadelphia to Saratoga (California) | 2,508.58 mi (4,037.17 km) |
| Philadelphia to Saratoga Springs (New York) | 222.73 mi (358.45 km) |
| Philadelphia to Saratoga Springs (Utah) | 1,927.70 mi (3,102.33 km) |
| Philadelphia to Sartell (Minnesota) | 1,038.99 mi (1,672.09 km) |
| Philadelphia to Satellite Beach (Florida) | 874.69 mi (1,407.67 km) |
| Philadelphia to Sauk Rapids (Minnesota) | 1,035.50 mi (1,666.47 km) |
| Philadelphia to Sault Ste. Marie (Michigan) | 644.38 mi (1,037.02 km) |
| Philadelphia to Savage (Minnesota) | 983.93 mi (1,583.48 km) |
