| Philadelphia to Scottsboro (Alabama) | 704.19 mi (1,133.29 km) |
| Philadelphia to Scottsdale (Arizona) | 2,062.06 mi (3,318.57 km) |
| Philadelphia to Scranton (Pennsylvania) | 100.43 mi (161.63 km) |
| Philadelphia to Seabrook (Maryland) | 115.82 mi (186.39 km) |
| Philadelphia to Seabrook (Texas) | 1,334.33 mi (2,147.39 km) |
| Philadelphia to Seaford (New York) | 97.75 mi (157.31 km) |
| Philadelphia to Seagoville (Texas) | 1,291.40 mi (2,078.31 km) |
| Philadelphia to Seal Beach (California) | 2,388.52 mi (3,843.95 km) |
| Philadelphia to Searcy (Arkansas) | 964.51 mi (1,552.23 km) |
| Philadelphia to Seaside (California) | 2,512.80 mi (4,043.97 km) |
| Philadelphia to SeaTac (Washington) | 2,372.23 mi (3,817.74 km) |
| Philadelphia to Seattle (Washington) | 2,372.35 mi (3,817.93 km) |
| Philadelphia to Sebastian (Florida) | 898.18 mi (1,445.48 km) |
| Philadelphia to Sebring (Florida) | 938.15 mi (1,509.81 km) |
| Philadelphia to Secaucus (New Jersey) | 77.54 mi (124.79 km) |
