| Philadelphia to Security-Widefield (Colorado) | 1,574.95 mi (2,534.63 km) |
| Philadelphia to Sedalia (Missouri) | 969.47 mi (1,560.21 km) |
| Philadelphia to Sedro-Woolley (Washington) | 2,363.50 mi (3,803.69 km) |
| Philadelphia to Seguin (Texas) | 1,475.77 mi (2,375.02 km) |
| Philadelphia to Selden (New York) | 124.93 mi (201.06 km) |
| Philadelphia to Selma (Alabama) | 844.35 mi (1,358.84 km) |
| Philadelphia to Selma (California) | 2,398.85 mi (3,860.58 km) |
| Philadelphia to Selma (Texas) | 1,492.84 mi (2,402.49 km) |
| Philadelphia to Seminole (Florida) | 947.07 mi (1,524.16 km) |
| Philadelphia to Seven Hills (Ohio) | 355.38 mi (571.92 km) |
| Philadelphia to Seven Oaks (South Carolina) | 528.36 mi (850.32 km) |
| Philadelphia to Severn (Maryland) | 102.71 mi (165.29 km) |
| Philadelphia to Severna Park (Maryland) | 99.45 mi (160.05 km) |
| Philadelphia to Sevierville (Tennessee) | 540.20 mi (869.36 km) |
| Philadelphia to Seymour (Indiana) | 577.99 mi (930.18 km) |
