| Philadelphia to Storm Lake (Iowa) | 1,054.17 mi (1,696.52 km) |
| Philadelphia to Storrs (Connecticut) | 195.26 mi (314.24 km) |
| Philadelphia to Stoughton (Wisconsin) | 755.72 mi (1,216.21 km) |
| Philadelphia to Stow (Ohio) | 340.20 mi (547.50 km) |
| Philadelphia to Streamwood (Illinois) | 693.38 mi (1,115.89 km) |
| Philadelphia to Streator (Illinois) | 722.23 mi (1,162.31 km) |
| Philadelphia to Streetsboro (Ohio) | 336.61 mi (541.71 km) |
| Philadelphia to Strongsville (Ohio) | 362.32 mi (583.10 km) |
| Philadelphia to Stuart (Florida) | 932.33 mi (1,500.43 km) |
| Philadelphia to Stuarts Draft (Virginia) | 250.47 mi (403.09 km) |
| Philadelphia to Sturgis (Michigan) | 550.78 mi (886.40 km) |
| Philadelphia to Suamico (Wisconsin) | 732.93 mi (1,179.53 km) |
| Philadelphia to Sudley (Virginia) | 151.69 mi (244.12 km) |
| Philadelphia to Suffern (New York) | 92.47 mi (148.81 km) |
| Philadelphia to Suffolk (Virginia) | 242.96 mi (391.01 km) |
