| Philadelphia to Superior (Colorado) | 1,582.24 mi (2,546.37 km) |
| Philadelphia to Superior (Wisconsin) | 965.92 mi (1,554.50 km) |
| Philadelphia to Surprise (Arizona) | 2,093.25 mi (3,368.76 km) |
| Philadelphia to Susanville (California) | 2,372.58 mi (3,818.30 km) |
| Philadelphia to Sussex (Wisconsin) | 709.34 mi (1,141.57 km) |
| Philadelphia to Suwanee (Georgia) | 641.49 mi (1,032.38 km) |
| Philadelphia to Swansea (Illinois) | 799.73 mi (1,287.04 km) |
| Philadelphia to Sweetwater (Florida) | 1,028.58 mi (1,655.33 km) |
| Philadelphia to Sweetwater (Texas) | 1,495.47 mi (2,406.73 km) |
| Philadelphia to Sycamore (Illinois) | 718.88 mi (1,156.92 km) |
| Philadelphia to Sylacauga (Alabama) | 775.91 mi (1,248.71 km) |
| Philadelphia to Sylvania (Ohio) | 463.07 mi (745.24 km) |
| Philadelphia to Syosset (New York) | 102.40 mi (164.80 km) |
| Philadelphia to Syracuse (New York) | 215.97 mi (347.57 km) |
| Philadelphia to Syracuse (Utah) | 1,926.06 mi (3,099.70 km) |
