| Port Huron to Selargius | 4,521.74 mi (7,277.04 km) |
| Port Huron to Selvazzano Dentro | 4,381.80 mi (7,051.82 km) |
| Port Huron to Senago | 4,268.31 mi (6,869.18 km) |
| Port Huron to Senigallia | 4,506.81 mi (7,253.01 km) |
| Port Huron to Seravezza | 4,374.74 mi (7,040.46 km) |
| Port Huron to Seregno | 4,268.41 mi (6,869.34 km) |
| Port Huron to Seriate | 4,287.79 mi (6,900.53 km) |
| Port Huron to Sermoneta | 4,587.29 mi (7,382.53 km) |
| Port Huron to Serramanna | 4,504.53 mi (7,249.35 km) |
| Port Huron to Serravalle Pistoiese | 4,403.09 mi (7,086.09 km) |
| Port Huron to Sessa Aurunca | 4,639.65 mi (7,466.79 km) |
| Port Huron to Sesto Calende | 4,242.47 mi (6,827.60 km) |
| Port Huron to Sesto Fiorentino | 4,420.63 mi (7,114.32 km) |
| Port Huron to Sesto San Giovanni | 4,274.25 mi (6,878.74 km) |
| Port Huron to Sestri Levante | 4,329.76 mi (6,968.08 km) |
