| Port Huron to Sangeorgiu de Mures | 4,808.59 mi (7,738.67 km) |
| Port Huron to Sangeorz-Bai | 4,778.47 mi (7,690.20 km) |
| Port Huron to Sannicolau Mare | 4,691.02 mi (7,549.47 km) |
| Port Huron to Santana | 4,710.88 mi (7,581.42 km) |
| Port Huron to Satu Mare | 4,696.47 mi (7,558.24 km) |
| Port Huron to Scobinti | 4,855.94 mi (7,814.87 km) |
| Port Huron to Scornicesti | 4,903.08 mi (7,890.74 km) |
| Port Huron to Sebes | 4,803.53 mi (7,730.54 km) |
| Port Huron to Seini | 4,712.31 mi (7,583.73 km) |
| Port Huron to Sfantu-Gheorghe | 4,887.23 mi (7,865.24 km) |
| Port Huron to Sibiu | 4,832.14 mi (7,776.58 km) |
| Port Huron to Sighetu Marmatiei | 4,725.46 mi (7,604.89 km) |
| Port Huron to Sighisoara | 4,835.45 mi (7,781.91 km) |
| Port Huron to Simeria | 4,788.29 mi (7,706.00 km) |
| Port Huron to Sinaia | 4,902.85 mi (7,890.38 km) |
